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My company is trying to setup a new RF chamber (shield room , 12x12) from ets-lindgren. They offer two kinds of interiors - absorptive materiel with cone structure and another one without cones.
I need to know what the advantages of cone design inside the RF chamber and whats the disadvantage of not having a cone structure.
Please help. 

First of all, are you talking about a screen(lined) room or a semi-anechoic chamber with steel walls, lined with ferrite tiles?   What kind of gear are you testing?  Bluetooth?  802.11n?  Are you looking to run performance, compliance pre-testing, basic connectivity tests, or what exactly?

Absorbing cones in either room will cut down on reflections which is almost always a good thing.  But type and placement can be very important.

One of the worst parts of using cones is how much they cut down the amount of space inside the chamber.  Depending on your wall construction, and the cones you need for the frequencidies you are using, your 12x12 may end up more like an 8x8 or smaller.  Cones can also be very messy - as no matter how hard you try to prevent it, someone will always run into them and they'll tend to fall apart.   (ETS has a new cone type that can help in that regard.)

Just a note on multipath 802.11n (multi-stream) testing - other than basic connectivity or compliance testing, neither a screen room nor an anechoic chamber will give you a good test environment.  Semi-anechoic chambers, by design, are designed to have few reflections, and screen rooms generally have too many.

Please feel free to post any specific questions you have here too.

Where are you located?

Cheers.